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Chemical Structure : RP-6685
CAS No.: 2832047-80-8
Catalog No.: PC-49348Not For Human Use, Lab Use Only.
RP-6685 (RP6685) is a potent, selective and orally bioavailable inhibitor of DNA polymerase theta (Polθ) with IC50 of 5.8 nM in PicoGreen assay (0.3 nM Polθ enzyme).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg (Free Sample) | $28 | In stock | |
| 5 mg | $278 | In stock | |
| 10 mg | $428 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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| M.Wt | 497.377 | |
| Formula | C22H14F7N5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(3-(6-aminopyridazin-3-yl)prop-2-yn-1-yl)-2-(3,5-bis(trifluoromethyl)pyridin-2-yl)-N-(4-fluorophenyl)acetamide |
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1. Bubenik M, et al. J Med Chem. 2022 Oct 13;65(19):13198-13215.
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