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Chemical Structure : RSM-932A
Catalog No.: PC-60864Not For Human Use, Lab Use Only.
A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.0 uM, 33-fold selectivity over ChoKβ.
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A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.0 uM, 33-fold selectivity over ChoKβ; demonstrates potent in vitro antiproliferative (HT29 IC50=1.15 uM) and in vivo antitumoral activity against human xenografts in mice with low toxicity profiles.
Solid Tumors
Phase 1 Clinical
| M.Wt | 717.737 | |
| Formula | C46H38Cl2N42Br | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9.
2. Zimmerman T, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):5878-88.
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