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Chemical Structure : RSMI-29
Catalog No.: PC-22182Not For Human Use, Lab Use Only.
RSMI-29 is a small molecule inhibitor of ricin toxin, specifically targeting ricin toxin A chain (RTA) with binding KD of 0.9 uM, inhibits cytotoxicity of RTA/ricin.
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RSMI-29 is a small molecule inhibitor of ricin toxin, specifically targeting ricin toxin A chain (RTA) with binding KD of 0.9 uM, inhibits cytotoxicity of RTA/ricin.
RSMI-29 attenuates RTA/ricin-induced protein synthesis inhibition and rRNA depurination.
RSMI-29 (0.15 mg/kg) protects mice against ricin intoxication, reduces ricin-induced organ damage.
| M.Wt | 367.38 | |
| Formula | C14H17N5O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Xinran Yang, et al. Molecules. 2024 Mar 22;29(7):1435.
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