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Chemical Structure : RTC-30
Catalog No.: PC-62748Not For Human Use, Lab Use Only.
RTC-30 is an orally active, dual pathway inhibitor of PI3K-AKT and RAS-ERK signaling via putative activation of the tumor suppressor PP2A, exhibits GI50 of 15 uM against H1650 lung adenocarcinoma cells.
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RTC-30 is an orally active, dual pathway inhibitor of PI3K-AKT and RAS-ERK signaling via putative activation of the tumor suppressor PP2A, exhibits GI50 of 15 uM against H1650 lung adenocarcinoma cells.
RTC-30 significantly decrease tumor growth in H1650 xenograft in mice.
| M.Wt | 492.513 | |
| Formula | C24H23F3N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kastrinsky DB, et al. Bioorg Med Chem. 2015 Oct 1;23(19):6528-34.
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