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Chemical Structure : RUNX1-IN-17
Catalog No.: PC-61298Not For Human Use, Lab Use Only.
A potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays.
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A potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays; binds to CBFβ at a site displaced from the binding interface for Runx1; decreases proliferation in human leukemia cell line ME-1.
| M.Wt | 234.317 | |
| Formula | C12H14N2OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gorczynski MJ, et al. Chem Biol. 2007 Oct;14(10):1186-97.
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