RUNX1-IN-17

Chemical Structure : RUNX1-IN-17

CAS No.: 493028-20-9

Catalog No.: PC-61298Not For Human Use, Lab Use Only.

RUNX1-IN-17 is a potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays.

Packing	Price	Stock
10 mg	$128	In stock
25 mg	$198	In stock
50 mg	$298	In stock
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

RUNX1-IN-17 is a potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays.
RUNX1-IN-17 binds to CBFβ at a site displaced from the binding interface for Runx1.
RUNX1-IN-17 decreases proliferation in human leukemia cell line ME-1.

Physicochemical Properties

M.Wt	234.317
Formula	C12H14N2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-ethyl-4-(4-methoxyphenyl)thiazol-2-amine

References

1. Gorczynski MJ, et al. Chem Biol. 2007 Oct;14(10):1186-97.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

RUNX1-IN-17

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.