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RX 871024

Chemical Structure : RX 871024

CAS No.: 142872-84-2

RX 871024 (RX871024;RX-871024)

Catalog No.: PC-60559Not For Human Use, Lab Use Only.

RX 871024 is an imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RX 871024 is an imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells.
    RX 871024 blocks ATP-dependent K+ channels and membrane depolarization, and activates voltage-dependent Ca2+ channels.

    Physicochemical Properties

    M.Wt 297.78
    Formula C17H15N3 · HCl
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-1H-indole hydrochloride

    References

    1. Efanova IB, et al. Diabetes. 1998 Feb;47(2):211-8.

    2. Zaitsev SV, et al. Diabetes. 1996 Nov;45(11):1610-8.

    3. Mourtada M, et al. Eur J Pharmacol. 1998 Jun 5;350(2-3):251-8.

    4. Mourtada M, et al. Br J Pharmacol. 1999 Jul;127(5):1279-87.

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