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Ractopamine

Chemical Structure : Ractopamine

CAS No.: 97825-25-7

Ractopamine (LY031537 free base, LY-031537 free base)

Catalog No.: PC-61074Not For Human Use, Lab Use Only.

Ractopamine hydrochloride (LY031537) is a potent and orally active β-adrenergic receptor (βAR) agonist with Ki of 25 nM for pig β1AR and β2A, is also a TAAR1 agonist with EC50 of 16 uM for mTAAR1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Ractopamine hydrochloride (LY031537) is a potent and orally active β-adrenergic receptor (βAR) agonist with Ki of 25 nM for pig β1AR and β2A, is also a TAAR1 agonist with EC50 of 16 uM for mTAAR1.
    Ractopamine produces concentration-dependent increases in chloride conductance in oocytes coexpressing hCFTR and mTAAR1, which can be completely reversed by mTAAR1 antagonist EPPTB.

    Physicochemical Properties

    M.Wt 301.386
    Formula C18H23NO3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-[3-[[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]amino]butyl]phenol

    References

    1. Liu X, et al. J Pharmacol Exp Ther. 2014 Jul;350(1):124-9.

    2. Colbert WE, et al. J Pharm Pharmacol. 1991 Dec;43(12):844-7.

    3. Bunzow JR, et al. Mol Pharmacol. 2001 Dec;60(6):1181-8.

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