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Ractopamine hydrochloride

Chemical Structure : Ractopamine hydrochloride

CAS No.: 90274-24-1

Ractopamine hydrochloride

Catalog No.: PC-28374Not For Human Use, Lab Use Only.

Ractopamine hydrochloride (LY031537) is a potent and orally active β-adrenergic receptor (βAR) agonist with Ki of 25 nM for pig β1AR and β2A, is also a TAAR1 agonist with EC50 of 16 uM for mTAAR1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ractopamine hydrochloride (LY031537) is a potent and orally active β-adrenergic receptor (βAR) agonist with Ki of 25 nM for pig β1AR and β2A, is also a TAAR1 agonist with EC50 of 16 uM for mTAAR1.
Ractopamine produces concentration-dependent increases in chloride conductance in oocytes coexpressing hCFTR and mTAAR1, which can be completely reversed by mTAAR1 antagonist EPPTB.

Physicochemical Properties

M.Wt 337.84
Formula C18H24ClNO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[3-[[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]amino]butyl]phenol hydrochloride

References

1. Liu X, et al. J Pharmacol Exp Ther. 2014 Jul;350(1):124-9.

2. Colbert WE, et al. J Pharm Pharmacol. 1991 Dec;43(12):844-7.

3. Bunzow JR, et al. Mol Pharmacol. 2001 Dec;60(6):1181-8.

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