Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Ral inhibitor 1
Catalog No.: PC-38330Not For Human Use, Lab Use Only.
Ral inhibitor 1 is a covalent inhibitor of RalB (Ras-like GTPase) activation, inhibits guanine exchange factor Rgl2-mediated nucleotide exchange of Ral GTPase, selectively inhibits Ral over Ras.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Ral inhibitor 1 is a covalent inhibitor of RalB (Ras-like GTPase) activation, inhibits guanine exchange factor Rgl2-mediated nucleotide exchange of Ral GTPase, selectively inhibits Ral over Ras.
Ral inhibitor 1 inhibits RalB/Rgl2 interaction through covalent reaction at Tyr-82 with IC50 of 49.5 uM.
Ral (Ras-like) GTPases are directly activated by oncogenic Ras GTPases.
| M.Wt | 346.347 | |
| Formula | C12H11FN2O5S2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Khuchtumur Bum-Erdene, et al. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7131-7139.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
