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Chemical Structure : Retro 1
Catalog No.: PC-62657Not For Human Use, Lab Use Only.
Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.
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Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge.
| M.Wt | 373.25 | |
| Formula | C18H17BrN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Stechmann B, et al. Cell. 2010 Apr 16;141(2):231-42.
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