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Ru360

Chemical Structure : Ru360

CAS No.:

Ru360 (Ru-360;Ru 360;)

Catalog No.: PC-60650Not For Human Use, Lab Use Only.

A cell-permeable mitochondrial calcium uptake inhibitor that binds to mitochondria with high affinity (Kd=340 pM) and blocks Ca2+ uptake into mitochondria in vitro with IC50 of 184 pM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A cell-permeable mitochondrial calcium uptake inhibitor that binds to mitochondria with high affinity (Kd=340 pM) and blocks Ca2+ uptake into mitochondria in vitro with IC50 of 184 pM; inhibits the flow of calcium into mitochondria and prevents the opening of the mitochondrial permeability transition pore, improves cardiac post-ischaemic functional recovery in rats in vivo.

Physicochemical Properties

M.Wt 550.78
Formula C2H26N8O5Ru2•3Cl
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

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