Catalog No.: PC-24261Not For Human Use, Lab Use Only.
SARM1 inhibitor NB-7 is a potent, selective and uncompetitive inhibitor of the nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 with biochemical IC50 of 0.025 uM, and IC50 of 0.008 uM in SARM-induced cell-death rescue assays.
SARM1 inhibitor NB-7 is a potent, selective and uncompetitive inhibitor of the nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 with biochemical IC50 of 0.025 uM, and IC50 of 0.008 uM in SARM-induced cell-death rescue assays.
NB-7 potently protectes against axon degeneration with IC50 of 0.11 uM in cellular models of nerve injury.
