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Chemical Structure : SB1301
CAS No.: 2024548-03-4
Catalog No.: PC-62859Not For Human Use, Lab Use Only.
SB1301 (Lin28-IN-1) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 100 mg | Get quote |
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SB1301 (Lin28-IN-1) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.
SB1301 (Lin28-IN-1) enhances the production of let-7 miRNAs in Lin28-expressing cancer cells and reduces the level of let-7 target oncogene products.
| M.Wt | 583.601 | |
| Formula | C31H29N5O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-(7-(4-((benzyloxy)carbonyl)piperazin-1-yl)-4,4-dimethyl-8-nitrochromeno[4,3-c]pyrazol-1(4H)-yl)benzoic acid |
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1. Lim D, et al. J. Am. Chem. Soc., 2016, 138 (41), pp 13630–13638
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