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Chemical Structure : SB1501
Catalog No.: PC-20138Not For Human Use, Lab Use Only.
SB1501 (SB 1501) is a bioactive compound that reduces fat accumulation by elevating mitochondrial biogenesis and fatty acid oxidation via the PGC-1α-UCP1 pathway, shows anti-obesity effects in vivo.
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SB1501 (SB 1501) is a bioactive compound that reduces fat accumulation by elevating mitochondrial biogenesis and fatty acid oxidation via the PGC-1α-UCP1 pathway, shows anti-obesity effects in vivo.
SB1501 (40 μM) reduces the size and fat accumulation of lipid droplets (LDs) in 3T3-L1 adipocytes.
SB1501 increases mitochondrial biogenesis and fatty acid oxidation (FAO) with upregulation of PGC-1α-UCP1 regulatory axis, which leads to reduced fat accumulation and demand for lipid storage capacity in 3T3-L1 adipocyte.
SB1501 increases mitochondrial function and morphology in 3T3-L1 adipocytes.
SB1501 (10 mg/kg, 5 weeks, oral) exhibits anti-obesity effects in a db/db mouse model.
SB1501 significantly increased the mRNA levels of Pgc-1α and Ucp1 in inguinal white adipose tissue.
| M.Wt | 349.39 | |
| Formula | C20H19N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jo A, et al. ChemMedChem. 2021 Apr 8;16(7):1104-1115.
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