SB200646 | 5-HT2B/2C antagonist | Probechem Biochemicals

Chemical Structure : SB200646

CAS No.:

SB200646 (SB-200646A, SB-200646 hydrochloride)

Catalog No.: PC-27114Not For Human Use, Lab Use Only.

SB200646 (SB-200646A) is a potent, selective and orally active 5-HT2B/2C receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively, shows electrophysiological and anxiolytic properties.

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Biological Activity

Physicochemical Properties

M.Wt	302.76
Formula	C15H15ClN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(1-Methyl-1H-indol-5-yl)-3-(pyridin-3-yl)urea hydrochloride

References

1. Kennett GA, et al. Br J Pharmacol. 1994 Mar;111(3):797-802.

2. Jackson HC, et al. Br J Pharmacol. 1997 Aug;121(8):1613-8.

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SB200646 (SB-200646A, SB-200646 hydrochloride)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

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