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SBI-2130

Chemical Structure : SBI-2130

CAS No.: 2929401-67-0

SBI-2130 (SBI 2130, SBI2130)

Catalog No.: PC-38183Not For Human Use, Lab Use Only.

SBI-2130 (SBI 2130) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.22/5.0 uM for Wt SHP2/SHP2-E76K.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SBI-2130 (SBI 2130) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.22/5.0 uM for Wt SHP2/SHP2-E76K.

    Physicochemical Properties

    M.Wt 454.5
    Formula C26H18N2O4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (Z)-N-(4-aminophenyl)-2-hydroxy-5-(5-((3-oxobenzo[b]thiophen-2(3H)-ylidene)methyl)furan-2-yl)benzamide

    References

    1. Raveendra-Panickar D, et al. J Biol Chem. 2022 Jan;298(1):101477.

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