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SBI-993

Chemical Structure : SBI-993

CAS No.: 2073059-82-0

SBI-993 (SBI993)

Catalog No.: PC-61674Not For Human Use, Lab Use Only.

SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability.
SBI-993 reduces Txnip and Arrdc4 expression to a degree similar to that seen with SBI-477 in human myotubes.
SBI-993 reduces muscle and liver TAG levels, enhances insulin signaling, and improved glucose tolerance in mice fed a high-fat diet.

Physicochemical Properties

M.Wt 452.529
Formula C23H24N4O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(4-methoxyphenyl)thiazol-2-yl)-4-((2-morpholino-2-oxoethyl)amino)benzamide

References

1. Ahn B, et al. J Clin Invest. 2016 Sep 1;126(9):3567-79.

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