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Chemical Structure : SC57461A
CAS No.: 423169-68-0
Catalog No.: PC-70334Not For Human Use, Lab Use Only.
SC57461A (SC 57461A) is a potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $138 | In stock | |
| 25 mg | $238 | In stock | |
| 50 mg | $418 | In stock | |
| 100 mg | Get quote |
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SC57461A (SC 57461A) is a potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM.
SC57461A (SC 57461A) inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM).
SC57461A (SC 57461A) has no effect on production of the cyclooxygenase metabolite thromboxane B(2).
SC57461A (SC 57461A) is orally active in vivo.
| M.Wt | 363.88 | |
| Formula | C20H25NO3.HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-((3-(4-benzylphenoxy)propyl)(methyl)amino)propanoic acid hydrochloride |
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1. Askonas LJ, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):577-82.
2. Kachur JF, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):583-7.
3. Penning TD, et al. J Med Chem. 2002 Aug 1;45(16):3482-90.
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