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Chemical Structure : SCH 529074
Catalog No.: PC-62084Not For Human Use, Lab Use Only.
SCH 529074 is a small molecule mutant p53 reactivator that binds p53 DNA binding domain with Kd of 1-2 uM.
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SCH 529074 is a small molecule mutant p53 reactivator that binds p53 DNA binding domain with Kd of 1-2 uM; restores growth-suppressive function to mutant p53 and inhibits ubiquitination of p53 by HDM2.
| M.Wt | 563.6 | |
| Formula | C31H36Cl2N6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Demma M, et al. J Biol Chem. 2010 Apr 2;285(14):10198-212.
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