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Chemical Structure : SG85
Catalog No.: PC-63438Not For Human Use, Lab Use Only.
SG85 is a potent Enterovirus 3C protease inhibitor with EC50 of 180 nM against EV71 and 60 nM against human rhinovirus 14 in a live virus-cell-based assay.
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SG85 is a potent Enterovirus 3C protease inhibitor with EC50 of 180 nM against EV71 and 60 nM against human rhinovirus 14 in a live virus-cell-based assay; effectively inhibits the in vitro replication of 14 rhinoviruses representative of species A and B with mean EC50 of 40 nM, efficiently blocks rhinovirus replication and is not cross-resistant with rupintrivir.
| M.Wt | 650.773 | |
| Formula | C35H46N4O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tijsma A, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.
2. Tan J, et al. J Virol. 2013 Apr;87(8):4339-51.
3. Lacroix C, et al. Antimicrob Agents Chemother. 2015 Sep;59(9):5814-8.
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