SGSS05NS

Chemical Structure : SGSS05NS

Catalog No.: PC-26274Not For Human Use, Lab Use Only.

SGSS05NS is a potent, selective and covalent inhibitor of protein lysine methyltransferase (PKMT) SETD8 with IC50 of 0.54 uM, covalently modifies SETD8 at Cys311.

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Biological Activity

SGSS05NS is a potent, selective and covalent inhibitor of protein lysine methyltransferase (PKMT) SETD8 with IC50 of 0.54 uM, covalently modifies SETD8 at Cys311.

Physicochemical Properties

M.Wt	364.46
Formula	C21H20N2O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-methylpiperazin-1-yl)-3-(phenylthio)naphthalene-1,4-dione

References

1. Shi Chen, et al. Elife. 2019 May 13:8:e45403.

2. Patent WO2015172076A1.

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SGSS05NS

Biological Activity

Physicochemical Properties

References

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