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Chemical Structure : SHP2-IN-2
Catalog No.: PC-63257Not For Human Use, Lab Use Only.
SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant.
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SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant。
SHP2-IN-2 reduces the viability of MOLM14 cells with IC50 of 85 uM.
| M.Wt | 342.797 | |
| Formula | C17H11ClN2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. LaRochelle JR, et al. Bioorg Med Chem. 2017 Dec 15;25(24):6479-6485.
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