SIRT3 activator 31

Chemical Structure : SIRT3 activator 31

Catalog No.: PC-25603Not For Human Use, Lab Use Only.

SIRT3 activator 31 is a specific, cellular active small molecule activator of mitochondrial SIRT3 with binding KD of 32 uM, binds stronger to Sirt3 than to Sirt5.

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Biological Activity

SIRT3 activator 31 is a specific, cellular active small molecule activator of mitochondrial SIRT3 with binding KD of 32 uM, binds stronger to Sirt3 than to Sirt5.

Physicochemical Properties

M.Wt	495.53
Formula	C27H29NO8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	diethyl 4-phenyl-1-(3,4,5-trimethoxybenzoyl)-1,4-dihydropyridine-3,5-dicarboxylate

References

1. Suenkel B, et al. J Med Chem. 2022 Oct 27;65(20):14015-14031.

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