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Chemical Structure : SIRT3 inhibitor 8
Catalog No.: PC-72772Not For Human Use, Lab Use Only.
SIRT3 inhibitor 8 is a SIRT3 selective inhibitor with IC50 of 6 uM, 6.8- and 5.3-fold selectivity for SIRT3 versus SIRT1 and SIRT2.
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SIRT3 inhibitor 8 is a SIRT3 selective inhibitor with IC50 of 6 uM, 6.8- and 5.3-fold selectivity for SIRT3 versus SIRT1 and SIRT2.
SIRT3 inhibitor 8 reduced DLBCL cell viability and triggered activation of autophagy.
| M.Wt | 436.511 | |
| Formula | C28H24N2O3 | |
| Appearance | Solid | |
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1. Sumit S Mahajan, et al. J Med Chem. 2014 Apr 24;57(8):3283-94.
2. Meng Li, et al. Cancer Cell. 2019 Jun 10;35(6):916-931.e9.
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