SKF-91488 | HNMT inhibitor | Probechem Biochemicals

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Chemical Structure : SKF-91488

CAS No.: 68941-21-9

SKF-91488 (Homodimaprit, SKF 91488, SKF91488)

Catalog No.: PC-27382Not For Human Use, Lab Use Only.

SKF-91488 (Homodimaprit, SKF 91488) is a potent, noncompetitive histamine N-methyltransferase (HNMT) inhibitor with Ki of 0.9 uM, blocks histamine metabolism and increases histamine concentrations, can increase blood pressure and enhance bronchoconstriction.

Packing	Price	Stock
25 mg	$78	In stock
50 mg	$118	In stock
100 mg	$188	In stock
250 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	248.21
Formula	C7H19Cl2N3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(Dimethylamino)butyl carbamimidothioate dihydrochloride

References

1. Donaldson J, et al. Br J Pharmacol. 1986 Jan;87(1):191-9.

2. Poulakos JJ, et al. J Pharmacol Exp Ther. 1986 Dec;239(3):730-6.

3. Klein MC, et al. J Pharmacol Exp Ther. 1981 Feb;216(2):315-20.

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SKF-91488 (Homodimaprit, SKF 91488, SKF91488)

Biological Activity

Physicochemical Properties

References

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