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Chemical Structure : SMS121
Catalog No.: PC-22176Not For Human Use, Lab Use Only.
SMS121 (SMS-121) is a drug-like small molecule inhibitor of the very long/long chain fatty acid transporter CD36 (FAT, scavenger receptor class B member 3/SCARB3) with binding Kd of 5.57 uM.
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SMS121 (SMS-121) is a drug-like small molecule inhibitor of the very long/long chain fatty acid transporter CD36 (FAT, scavenger receptor class B member 3/SCARB3) with binding Kd of 5.57 uM.
SMS121 affects the viability of KG-1 cells with IC50 of 156 uM, impairs lipid uptake and reduce the viability in AML cells.
| M.Wt | 355.39 | |
| Formula | C20H21NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Åbacka H, et al. Sci Rep. 2024 Apr 20;14(1):9104.
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