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Chemical Structure : SOD1-Derlin-1 inhibitor 56-59
CAS No.: 2170170-27-9
Catalog No.: PC-35376Not For Human Use, Lab Use Only.
SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $358 | In stock | |
| 25 mg | $658 | In stock | |
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| 200 mg | Get quote | ||
| 1 g | Get quote |
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SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assays.
SOD1-Derlin-1 inhibitor 56-59 significantly ameliorates the ALS pathology both in motoneurons derived from patient induced pluripotent stem cells and in model mice.
| M.Wt | 386.473 | |
| Formula | C22H18N4OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-allyl-3-amino-N-phenyl-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide |
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1. Tsuburaya N, et al. Nat Commun. 2018 Jul 10;9(1):2668.
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