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Chemical Structure : SR9238
CAS No.: 1416153-62-2
Catalog No.: PC-63083Not For Human Use, Lab Use Only.
SR9238 is the first selective synthetic LXR inverse agonist with IC50 of 214 nM and 43 nM for LXRα and LXRβ, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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SR9238 is the first selective synthetic LXR inverse agonist with IC50 of 214 nM and 43 nM for LXRα and LXRβ, respectively.
SR9238 displays high potency for both LXRα and LXRβ (IC50=40-200 nM).
SR9238 suppresses plasma cholesterol levels in diet-induced obese mice.
| M.Wt | 595.7 | |
| Formula | C31H33NO7S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
ethyl 5-(((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenyl)sulfonamido)methyl)furan-2-carboxylate |
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1. Griffett K, et al. ACS Chem Biol. 2013 Mar 15;8(3):559-67.
2. Griffett K, et al. Mol Metab. 2015 Feb 9;4(4):353-7.
3. Griffett K, et al. Biochem Biophys Res Commun. 2016 Oct 21;479(3):424-428.
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