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Chemical Structure : SR9243
CAS No.: 1613028-81-1
Catalog No.: PC-45108Not For Human Use, Lab Use Only.
SR9243 is a potent LXR inverse agonist that inhibits LXR activation by enhancing LXR-corepressor recruitment.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $68 | In stock | |
| 25 mg | $118 | In stock | |
| 50 mg | $188 | In stock | |
| 100 mg | Get quote |
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SR9243 is a potent LXR inverse agonist that inhibits LXR activation by enhancing LXR-corepressor recruitment.
SR9243 potently reduces cancer cell viability in MTT reduction assays in prostate and lung cancer cells (IC50=15-104 nM).
SR9243 inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression.
| M.Wt | 626.6241 | |
| Formula | C31H32BrNO4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzenesulfonamide, N-[2-(3-bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]- |
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1. Griffett K, et al. ACS Chem Biol. 2013 Mar 15;8(3):559-67.
2. Flaveny CA, et al. Cancer Cell. 2015 Jul 13;28(1):42-56.
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