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SST0871AA1

Chemical Structure : SST0871AA1

CAS No.: 2245102-65-0

SST0871AA1

Catalog No.: PC-73269Not For Human Use, Lab Use Only.

SST0871AA1 is a small molecule Heparanase (Hpse) inhibitor with IC50 of 0.64 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SST0871AA1 is a small molecule Heparanase (Hpse) inhibitor with IC50 of 0.64 uM.
SST0871AA1 decreases the in vitro invasive ability of human cancer cell lines.
SST0871AA1 inhibits expression of genes encoding for proangiogenic factors such as MMP-9, VEGF, and FGFs in tumor cells.
SST0871AA1 does not affect cell proliferation.

Physicochemical Properties

M.Wt 660.500
Formula C32H27BrFN5O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. Madia, V. N. et al. J. Med. Chem. 2018, 61, 6918– 6936.

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