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Chemical Structure : SST0872AA1
Catalog No.: PC-73270Not For Human Use, Lab Use Only.
SST0872AA1 is a potent, small molecule Heparanase (Hpse) inhibitor with IC50 of 0.08 uM.
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SST0872AA1 is a potent, small molecule Heparanase (Hpse) inhibitor with IC50 of 0.08 uM.
SST0872AA1 inhibits the invasive ability of human CME-1 synovial sarcoma cells, does not affect cell proliferation.
SST0872AA1 decreases the mRNA levels of genes encoding for proangiogenic factors, such as FGF1/2, VEGF, and MMP-9, and for Hpse (HPSE-1).
| M.Wt | 728.684 | |
| Formula | C35H26F2N6O8S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Antonella Messore, et al. J Med Chem. 2018 Dec 13;61(23):10834-10859.
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