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ST101036

Chemical Structure : ST101036

CAS No.: 1018143-39-9

ST101036

Catalog No.: PC-27345Not For Human Use, Lab Use Only.

ST101036 is a small molecule mast cell activator (MCA), induces mouse BMMCs degranulation about 91% at 100 uM, and 38% in human LAD2 cells, promotes de novo synthesis of cytokines and induce the release of eicosanoids from mouse MCs.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ST101036 is a small molecule mast cell activator (MCA), induces mouse BMMCs degranulation about 91% at 100 uM, and 38% in human LAD2 cells, promotes de novo synthesis of cytokines and induce the release of eicosanoids from mouse MCs.

Physicochemical Properties

M.Wt 350.39
Formula C18H21F3N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[6-(4-ethylphenyl)-4-(trifluoromethyl)pyrimidin-2-yl]-4-piperidylamine

References

1. Choi HW, et al. SLAS Discov. 2019 Jul;24(6):628-640.

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