Chemical Structure : STIMA 1
Catalog No.: PC-62083Not For Human Use, Lab Use Only.
STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro, induces expression of p53 target proteins and triggers apoptosis in mutant p53-expressing human tumor cells..
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STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro, induces expression of p53 target proteins and triggers apoptosis in mutant p53-expressing human tumor cells.
M.Wt | 172.187 | |
Formula | C10H8N2O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Zache N, et al. Mol Oncol. 2008 Jun;2(1):70-80.
2. Bykov VJ, et al. FEBS Lett. 2014 Aug 19;588(16):2622-7.
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