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Chemical Structure : STK16-IN-1
CAS No.: 1223001-53-3
Catalog No.: PC-62875Not For Human Use, Lab Use Only.
STK16-IN-1 is a potent, highly selective ATP competitive STK16 inhibitor with IC50 of 0.295 uM, displays excellent selectivity across the kinome.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $228 | In stock | |
| 100 mg | $558 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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STK16-IN-1 is a potent, highly selective ATP competitive STK16 inhibitor with IC50 of 0.295 uM, displays excellent selectivity across the kinome.
STK16-IN-1 treatment results in a reduction in cell number and accumulation of binucleated cells after treatment in MCF-7 cells.
Co-treatment of STK16-IN-1 with chemotherapeutics such as cisplatin, doxorubicin, colchicine, and paclitaxel results in a slight potentiation of the antiproliferative effects of the chemotherapeutics.
| M.Wt | 293.301 | |
| Formula | C17H12FN3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-(4-Fluoro-3-methylphenyl)-1,7-dihydro-2H-pyrrolo[2,3-h]-1,6-naphthyridin-2-one |
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1. Liu F, et al. ACS Chem Biol. 2016 Jun 17;11(6):1537-43.
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