STK947495 | NPM1 oligomerization inhibitor

Chemical Structure : STK947495

STK947495 (STK-947495)

Catalog No.: PC-27709Not For Human Use, Lab Use Only.

STK947495 is a small-molecule modulator of Nucleophosmin 1 (NPM1) oligomerization, promotes dissociation of NPM1 oligomers, reduces NPM1 oligomerization in both lysate-based split luciferase and biochemical assays.

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Biological Activity

STK947495 is a small-molecule modulator of Nucleophosmin 1 (NPM1) oligomerization, promotes dissociation of NPM1 oligomers, reduces NPM1 oligomerization in both lysate-based split luciferase and biochemical assays.

Physicochemical Properties

M.Wt	326.37
Formula	C17H14N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(3-((4-(2,4-dihydroxyphenyl)thiazol-2-yl)amino)phenyl)ethan-1-one

References

1. Ozawa SI, et al. Comput Biol Chem. 2026 Jul 30;125:109291.

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STK947495 (STK-947495)

Biological Activity

Physicochemical Properties

References

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