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Chemical Structure : STS66
Catalog No.: PC-72596Not For Human Use, Lab Use Only.
STS66 is a novel BBB-penetrant Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, reduces brain damage in mice after ischemic stroke.
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STS66 is a novel BBB-penetrant Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, reduces brain damage in mice after ischemic stroke.
STS66 treatment completely blocked the ischemia-induced elevation of pNKCC1, which is superior to BMT and STS5.
STS66 showed efficacy against permanent focal ischemic brain injury with hypertension comorbidity.
| M.Wt | 431.474 | |
| Formula | C19H24F3N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Huachen Huang, et al. Stroke. 2019 Apr;50(4):1021-1025.
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