| Cat. No. |
Product Name |
Information |
| PC-72596 |
STS66
NKCC1 inhibitor
|
STS66 is a novel BBB-penetrant Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, reduces brain damage in mice after ischemic stroke. |
| PC-72424 |
ARN23746
NKCC1 inhibitor
|
ARN23746 (ARN-23746) is a potent, selective inhibitor of Na+-K+-Cl- importer NKCC1, shows NKCC1 inhibition 31.8% at 10 uM, and 95.2% at 100 uM in the Cl− influx assay on NKCC1-transfected HEK293 cells. |
| PC-45286 |
Bumetanide
NKCC inhibitor
|
Bumetanide (Ro 10-6338, PF-1593) is an inhibitor of Na(+)-K(+)-2Cl(-) co-transporter (NKCC) with an IC50 of 0.6 uM. |
| PC-72425 |
ARN24092
NKCC1 inhibitor
|
ARN24092 (ARN-4092) is a potent, selective inhibitor of Na+-K+-Cl- importer NKCC1, shows significant dose-dependent inhibition of NKCC1 in the Ca2+ influx assay (51.9% at 100 uM). |
| PC-35345 |
Azosemide
|
Azosemide (Azosemidum) is a potent Na-K-Cl Cotransporter NKCC1 with IC50 of 0.246 and 0.197 uM for hNKCC1A and NKCC1B, being about 4-times more potent than bumetanide. |
