Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : SU0268
CAS No.: 2210228-45-6
Catalog No.: PC-72024Not For Human Use, Lab Use Only.
SU0268 (SU 0268) is a potent, selective, noncovalent inhibitor DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) with IC50 of 59 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $288 | In stock | |
| 50 mg | $858 | In stock | |
| 100 mg | $1480 | In stock | |
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SU0268 (SU 0268) is a potent, selective, noncovalent inhibitor DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) with IC50 of 59 nM.
SU0268 displays low or negligible inhibition against other repair enzymes MTH1, dUTPase, NUDT16, hABH2, hABH3, SMUG1 at 20 uM.
SU0268 shows good membrane permeability and no cytotoxicity in HEK293T and HeLa cells at active concentrations and demonstrates activity in inhibiting the enzyme in human cell lines.
SU0268 is a potentially useful tool in studies of the role of OGG1 in multiple disease-related pathways.
| M.Wt | 475.563 | |
| Formula | C26H25N3O4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
|
|
| Chemical Name/SMILES |
|
|
1. Yu-Ki Tahara, et al. J Am Chem Soc. 2018 Feb 14;140(6):2105-2114.
2. Qin S, et al. J Immunol. 2020 Oct 15;205(8):2231-2242.
3. Zhang L, et al. Redox Biol. 2021 Apr;40:101848.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
