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SYNTi

Chemical Structure : SYNTi

CAS No.:

SYNTi

Catalog No.: PC-20346Not For Human Use, Lab Use Only.

SYNTi is a small molecule PDZ domain inhibitor targeting the syndecan/syntenin protein-protein interaction with IC50 of 400 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SYNTi is a small molecule PDZ domain inhibitor targeting the syndecan/syntenin protein-protein interaction with IC50 of 400 nM.

Physicochemical Properties

M.Wt 567.41
Formula C28H24BrFN2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

((S)-3-(5'-acetyl-2'-fluoro-[1,1'-biphenyl]-4-yl)-2-(6-bromo-3-oxoindolin-1-yl)propanoyl)-L-alanine

References

1. Laurent Hoffer, et al. J Med Chem. 2023 Mar 20. doi: 10.1021/acs.jmedchem.2c01569.

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