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Salinomycin sodium

Chemical Structure : Salinomycin sodium

CAS No.: 55721-31-8

Salinomycin sodium (Sodium salinomycin)

Catalog No.: PC-45261Not For Human Use, Lab Use Only.

A polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration.

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Biological Activity

A polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration; inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells; induces ER stress‑mediated autophagy and apoptosis through generation of ROS in human glioma U87MG cells.

Physicochemical Properties

M.Wt 772.9804
Formula C42H69NaO11
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 15 mg/mL

Chemical Name/SMILES

Salinomycin, sodium salt (1:1)

References

1. Mitani M, et al. Antimicrob Agents Chemother. 1976 Apr;9(4):655-60.

2. Lu D, et al. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7.

3. Yu SN, et al. Oncol Rep. 2017 Jun;37(6):3321-3328.

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