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Chemical Structure : Satraplatin
CAS No.: 129580-63-8
Catalog No.: PC-45364Not For Human Use, Lab Use Only.
Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock | |
| 500 mg | Get quote |
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Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis; shows similar cytotoxicity and pattern of cytotoxicity to cisplatin against human ovarian carcinoma cell lines (IC50=1.7 uM); shows antitumor selectivity far superior to cisplatin, carboplatin, or tetraplatin in vivo; orally active.
Chemotherapeutic Agents
Phase 2 Clinical
| M.Wt | 500.2816 | |
| Formula | C10H22Cl2N2O4Pt+2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 33 mg/mL |
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| Chemical Name/SMILES |
Platinum, bis(acetato-κO)amminedichloro(cyclohexanamine)-, (OC-6-43)- (9CI) |
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1. Kelland LR, et al. Cancer Res. 1993 Jun 1;53(11):2581-6.
2. Mellish KJ, et al. Br J Cancer. 1993 Aug;68(2):240-50.
3. Ricart AD, et al. Clin Cancer Res. 2009 Jun 1;15(11):3866-71.
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