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Chemical Structure : Sepin-1
Catalog No.: PC-62753Not For Human Use, Lab Use Only.
Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM.
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Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM; inhibits the growth of human cancer cell lines and breast cancer xenograft tumors in mice by inhibiting cell proliferation and inducing apoptosis.
| M.Wt | 223.188 | |
| Formula | C9H9N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Do HT, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4446-50.
2. Zhang N, et al. J Biomol Screen. 2014 Jul;19(6):878-89.
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