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Chemical Structure : Shz-1
CAS No.: 326886-05-9
Catalog No.: PC-70268Not For Human Use, Lab Use Only.
Shz-1 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $348 | In stock | |
| 100 mg | Get quote |
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Shz-1 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
Shz-1 triggers cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells, including human mobilized peripheral blood mononuclear cells (M-PBMCs).
Shz-1 displays cardioregenerative activity as xenografts in injured immunocompromised rat heart.
| M.Wt | 355.21 | |
| Formula | C13H11BrN2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzenesulfonic acid, [(5-bromo-2-hydroxyphenyl)methylene]hydrazide (9CI) |
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1. Sadek H, et al. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6063-8.
2. Nan C, et al. Cardiovasc Toxicol. 2015 Jan;15(1):29-40.
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