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Chemical Structure : Shz-3
Catalog No.: PC-70267Not For Human Use, Lab Use Only.
Shz-3 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
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Shz-3 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
Shz-3 triggers cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells, including human mobilized peripheral blood mononuclear cells (M-PBMCs).
Shz-3 displays cardioregenerative activity as xenografts in injured immunocompromised rat heart.
| M.Wt | 290.337 | |
| Formula | C14H14N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sadek H, et al. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6063-8.
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