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Chemical Structure : Siastatin B
Catalog No.: PC-21646Not For Human Use, Lab Use Only.
Siastatin B is a potent and effective iminosugar inhibitor of diverse glycosidase classes, namely, sialidases, β-d-glucuronidases, and N-acetyl-glucosaminidases.
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Siastatin B is a potent and effective iminosugar inhibitor of diverse glycosidase classes, namely, sialidases, β-d-glucuronidases, and N-acetyl-glucosaminidases.
Siastatin B is a bacterial neuraminidase inhibitor isolated from Streptomyces culture.
Siastatin B also inhibits human cytosolic sialidase (Neuraminidase 2, NEU2).
| M.Wt | 218.21 | |
| Formula | C8H14N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nishimura Y, et al. J Antibiot (Tokyo). 1993 Dec;46(12):1883-9.
2. Rahman MM, et al. Biochem Biophys Rep. 2015 Sep 25;4:234-242.
3. Chen Y, et al. J Am Chem Soc. 2023 Dec 20. doi: 10.1021/jacs.3c04162.
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