Simotinib |CAS:944258-89-3 Probechem Biochemicals

Chemical Structure : Simotinib

Catalog No.: PC-63474Not For Human Use, Lab Use Only.

Simotinib (SIM-6802) is a novel potent, selective and orally bioavailable EGFR inhibitor with IC50 of 19.9 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Simotinib (SIM-6802) is a novel potent, selective and orally bioavailable EGFR inhibitor with IC50 of 19.9 nM.

M.Wt	500.95
Formula	C25H26ClFN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-chloro-4-fluorophenyl)-6-(2-(5,8-dioxa-11-azadispiro(2.0.4.3)undec-11-yl)ethoxy)-7-methoxy-4-quinazolinamine

1. Huang L, et al. Anticancer Drugs. 2016 Apr;27(4):300-11.