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Chemical Structure : Sinefungin
Catalog No.: PC-62408Not For Human Use, Lab Use Only.
Sinefungin (A 9145.
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Sinefungin (A 9145;RP 32232) is a non-selective inhibitor of SET domain-containing methyltransferases in the study of epigenetic regulation (IC50 values range from 0.1-20 uM); a nucleoside structurally related to S-adenosylhomocysteine and S-adenosylmethionine that isolated from Streptomyces; demonstrates high in vivo toxicity.
| M.Wt | 381.4 | |
| Formula | C15H23N7O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tisi D, et al. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105.
2. van Haren MJ, et al. Biochemistry. 2016 Sep 20;55(37):5307-15.
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