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Chemical Structure : Sofosbuvir
CAS No.: 1190307-88-0
Catalog No.: PC-21356Not For Human Use, Lab Use Only.
Sofosbuvir (GS-7977, PSI-7977) is a prodrug of 2'-F-2'-C-methyluridine monophosphate and HCV NS5B polymerase inhibitor, is active against GT 1a, 1b, and 2a (strain JFH-1) replicons and chimeric replicons containing GT 2a (strain J6), 2b, and 3a NS5B polymerase.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $178 | In stock | |
| 100 mg | $288 | In stock | |
| 200 mg | $428 | In stock | |
| 1 g | Get quote |
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Sofosbuvir (GS-7977, PSI-7977) is a prodrug of 2'-F-2'-C-methyluridine monophosphate and HCV NS5B polymerase inhibitor, is active against GT 1a, 1b, and 2a (strain JFH-1) replicons and chimeric replicons containing GT 2a (strain J6), 2b, and 3a NS5B polymerase.
| M.Wt | 529.46 | |
| Formula | C22H29FN3O9P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-Isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate |
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1. Lam AM, et al. Antimicrob Agents Chemother. 2012 Jun;56(6):3359-68.
2. Sofia MJ, et al. J Med Chem. 2010 Oct 14;53(19):7202-18.
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