Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Spindlactone A
Catalog No.: PC-61360Not For Human Use, Lab Use Only.
A novel small molecule inhibitor of transforming acidic coiled-coil-containing protein 3 (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A novel small molecule inhibitor of transforming acidic coiled-coil-containing protein 3 (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells; binds to and inhibits the function of the TACC3-TOGp complex, induces aberrant spindles in SKOV-3 cells, with no affect for spindle assembly in normal cells; selectively induces mitotic arrest in ovarian cancer cells.
| M.Wt | 447.487 | |
| Formula | C26H25NO6 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Yao R, et al. Oncogene. 2014 Aug 14;33(33):4242-52.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
