Sulfasalazine | SLC7A11/xCT inhibitor | Probechem Biochemicals

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Chemical Structure : Sulfasalazine

CAS No.: 599-79-1

Sulfasalazine (NSC 667219)

Catalog No.: PC-26734Not For Human Use, Lab Use Only.

Sulfasalazine (NSC 667219) is a disease-modifying antirheumatic drug used to treat arthritis and ankylosing spondylitis, is a SLC7A11/xc(-) cystine/glutamate antiporter (xCT) inhibitor, has anti-leukemic activity against primary AML samples.

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500 mg	$28	In stock
1 g	$38	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	398.39
Formula	C18H14N4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Hydroxy-5-((4-(N-(pyridin-2-yl)sulfamoyl)phenyl)diazenyl)benzoic acid

References

1. Nielsen OH, et al. Aliment Pharmacol Ther. 1988 Jun;2(3):203-11.

2. Berry CN, et al. Br J Pharmacol. 1988 Mar;93(3):465-72.

3. Hellewell PG, et al. Br J Pharmacol. 1982 Jun;76(2):319-26.

4. Pardieu B, et al. Leukemia. 2022 Jun;36(6):1585-1595.

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Sulfasalazine (NSC 667219)

Biological Activity

Physicochemical Properties

References

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